| Date | Lecture | Paper(s) |
| Jan. 12th | class introduction phenylketonuria (PKU) |
[1999] PNAS v. 96 pp. 2339-2344 (Sarkissian) [1999] PNAS v. 96 pp. 1811-813 (Comentary on Sarkissian by Levy) [2008] PNAS v. 105 pp. 20894-20899 (Sarkissian) |
| Jan. 19th | no class (Gordon Conference) | |
| Jan. 26th | hyperuricemia (gout) |
[2006] Nature v. 440
pp. 237-241 (Martinon) [2007] Joint Bone Spine v. 74 pp. 571-576 (Pétrilli Review) |
| Feb. 2nd | Niemann-Pick type C | [2008] Nature Medicine v. 14 pp. 1247-1255 (Lloyd-Evans et.al.) [2005] J. Biol. Chem. v. 280 pp. 20917-20920 (Chang et. al. Review) [2006] FEBS Letters v. 580 pp. 5518-5524 (Vance Review) [2008] Expert Rev. Mol. Med. v. 10 doi:10.1017/S146239940800080X (Pacheco et. al. Review) |
| Feb. 9th | sucrase-isomaltase deficiency | [2006] J. Biol. Chem. v. 281 pp. 14393-14399 (Keiser et. al.) |
| Feb. 16th | cystic fibrosis | [2004] Nature Medicine v. 10 pp. 487-493 (Frizzell et. al.) [2004] Nature Medicine v. 10 pp. 452-454 (Commentary on Frizzell et. al. by Mall et. al.) [2007] Drug Discov. Today Dis. Mech. v. 4 pp. 63-72 (Clunes and Boucher Review) |
| Feb. 23rd | Duchenne muscular dystrophy | [2007] Pediatric Neurology v. 36 pp. 1-7 (Deconinck and Dan, Review) [2008] Genes and Development v. 22 pp. 1747-1752 (Vidal et. al.) |
| Mar. 2nd | Class Canceled Due to Snow | |
| Mar. 9th | no class (Spring Break) | |
| Mar. 16th | ECM disorders (Marfan syndrome) | [2006] Science v. 312 pp. 117-121 (Habashi, et. al.) [2006] Science v. 312 pp. 36-37 (Commentary on Habashi et. al. by Travis) [2007] Curr. Opin. Genet. Dev. v. 17 pp. 252-258 (Ramirez and Dietz, Review) |
| Mar. 23rd | Alzheimer's Disease | [2008] J. Biol. Chem. v. 283 pp. 29645-29649 (Leissring, Review) [2008] Neuron v. 60 pp. 247-257 (Sun et. al.) |
| Mar. 30th | prions (Creuzfeldt-Jacob) | [2007] Nature v. 447 pp. 556-561 (Tessier & Lindquist) [2007] Nature v. 447 pp. 541-542 (Commentary on Tessier & Lindquist by Surewicz) [2009] Biochemistry v. 48 pp. 2574-2585 (Cobb & Surewicz, Review) |
| Apr. 6th | M. tuberculosis | [2003] Microbes & Infection v. 5 pp. 159-167 (Zahrt, Review) [2004] Cell v. 119 pp. 753-766 (Gutierrez et. al.) [2005] Cell v. 120 pp. 159-162 (Levine, minireview) |
| Apr. 13th | HIV | [2003] Nature v. 424 pp. 21-22 (Gu & Sundquist, News & Views) [2003] Nature v. 424 pp. 94-98 (Zhang et. al.) [2003] Nature v. 424 pp. 99-103 (Mangeat et. al.) |
| Apr. 20th | HIV paper / exam review | |
| Apr. 27th | comprehensive final exam | |
| Apr. 30th | special topics and wrap-up | |